1 p.m. ET games
Offense
Julio Jones, WR, ATL: Hamstring -- OUT
Impact: Calvin Ridley and Russell Gage will once again lead the Falcons through the air.
Marquise Brown, WR, BAL: Knee -- Active
Impact: Brown and fellow WR Dez Bryant are active, but RB Mark Ingram II again sits.
Cordarrelle Patterson, WR, CHI: Knee -- Active
Impact:, David Montgomery's fantasy output is unlikely to be affected.
Allen Robinson II, WR, CHI: Hamstring -- Active
Impact: Limited practice on Friday, but will give it a go..
Tyler Boyd, WR, CIN: Concussion -- OUT
Impact: A.J. Green could see a few more targets than usual.
Jarvis Landry, WR, CLE: Illness -- OUT/IR
Impact: Landry, Rashard Higgins, Donovan Peoples-Jones and KhaDarel Hodge are all on the reserve/COVID-19 list. Marvin Hall is the last receiver on the team's depth chart to start the week. Ja'Marcus Bradley and Derrick Willies have been elevated from the practice squad.
Duke Johnson, RB, HOU: Neck -- OUT
Impact: David Johnson may once again shine in a dual-purpose role.
Marcus Johnson, WR, IND: Quad -- OUT
Impact: Potential boon for longshot WR options Ashton Dulin/DeMichael Harris.
James Robinson, RB, JAX: Ankle -- OUT
Impact: Dare Ogunbowale and Devine Ozigbo will split carries behind QB Mike Glennon.
Collin Johnson, WR, JAX: Hamstring -- OUT
Impact: Keelan Cole might stumble into a few quality targets.
Clyde Edwards-Helaire, RB, KC: Ankle -- OUT
Impact: Le'Veon Bell/Darrel Williams to fill in for the rest of the regular season.
Tyreek Hill, WR, KC: Hamstring -- Active
Impact: Will start, though if the score allows, he may well get an early hook.
Daniel Jones, QB, NYG: Ankle -- Active
Impact: Will start, but is far from being at 100%.
Golden Tate, WR, NYG: Calf -- OUT
Impact: Sterling Shepard and Darius Slayton will attempt to lift the fortunes of a languid offense.
Chris Boswell, K, PIT: Groin -- Inactive
Impact: Matthew Wright will step in again for the injured kicker
Defense
Darqueze Dennard, CB, ATL: Quad -- OUT
Ricardo Allen, S, ATL: Concussion -- Active
Calais Campbell, DE, BAL: Calf -- Active
Pernell McPhee, LB, BAL: Knee -- Active
Jimmy Smith, CB, BAL: Shoulder -- OUT
Marcus Peters, CB, BAL: Calf -- Inactive
Akiem Hicks, DE, CHI: Ankle -- Active
Mario Edwards, DE, CHI: Hamstring -- Active
Bilal Nichols, DE, CHI: Knee -- Active
Khalil Mack, LB, CHI: Shoulder -- Active
Jaylon Johnson, CB, CHI: Shoulder -- OUT
Logan Wilson, LB, CIN: Ankle -- OUT
Sheldon Richardson, DT, CLE: Neck -- Active
Phillip Gaines, CB, HOU: Knee -- Inactive
Frank Clark, DE, KC: Illness -- Active
Damien Wilson, LB, KC: Knee -- OUT
Blake Martinez, LB, NYG: Ankle -- Active
Darnay Holmes, CB, NYG: Knee -- Active
4 p.m. ET games
Offense
Christian McCaffrey, RB, CAR: Thigh -- Doubtful
Impact: Not yet ruled out, but all signs point to another missed week.
Ezekiel Elliott, RB, DAL: Calf -- Questionable
Impact: Limited in practice this week. Likely to split time with Tony Pollard if active.
Blake Bell, TE, DAL: Illness -- Questionable
Impact: Dalton Schultz has shown flashes of fantasy relevance this season.
Phillip Lindsay, RB, DEN: Hip -- OUT/IR
Impact: Melvin Gordon III likely to get most, if not all, of the workload ....
Royce Freeman, RB, DEN: Hip -- Questionable
Impact: ... as Freeman is also nowhere near full capacity.
Keenan Allen, WR, LAC: Hamstring -- Questionable
Impact: Nowhere near a guaranteed start, Allen did practice a little bit on Friday. Better to assume he will not play.
Hunter Henry, TE, LAC: Illness -- OUT/IR
Impact: Henry is on the reserve/COVID-19 list. Stephen Anderson is not exactly screaming "pick me" as a replacement.
Cam Akers, RB, LAR: Ankle -- OUT
Impact: The tandem of Darrell Henderson and Malcolm Brown will try to shine in Week 16.
Alex Smith, QB, WAS: Calf -- Questionable
Impact: Looking more likely that Dwayne Haskins Jr. will start.
Antonio Gibson, RB, WAS: Toe -- Questionable
Impact: J.D. McKissic's value goes back on the upswing, even if Gibson were to play.
Terry McLaurin, WR, WAS: Ankle -- Doubtful
Impact: For what it's worth, Antonio Gandy-Golden was activated from the IR.
Defense
Brian Burns, DE, CAR: Knee -- Questionable
Bravvion Roy, DT, CAR: Knee -- Questionable
Troy Pride, CB, CAR: Hip -- Doubtful
Antwaun Woods, DT, DAL: Ankle -- OUT
Leighton Vander Esch, LB, DAL: Ankle -- OUT
Xavier Woods, S, DAL: Ribs -- OUT
DeShawn Williams, DT, DEN: Knee -- Questionable
Bradley Chubb, LB, DEN: Ankle -- Questionable
Nate Hairston, S, DEN: Toe -- Questionable
Joey Bosa, DE, LAC: Concussion -- OUT
Uchenna Nwosu, LB, LAC: Knee -- OUT
Fletcher Cox, DT, PHI: Neck -- Questionable
Derek Barnett, DE, PHI: Calf -- Questionable
Duke Riley, LB, PHI: Biceps -- OUT
Kevon Seymour, CB, PHI: Knee -- OUT
Kevin Pierre-Louis, LB, WAS: Ankle -- Questionable
Sunday night game
Jamaal Williams, RB, GB: Quad -- Doubtful
Impact: Aaron Jones (toe) is also a bit banged up but should be active and get the ball early and often.
Jace Sternberger, TE, GB: Concussion -- OUT
Impact: Robert Tonyan still the TE to roll with if you're looking Green Bay's way.
Offense
Julio Jones, WR, ATL: Hamstring -- OUT
Impact: Calvin Ridley and Russell Gage will once again lead the Falcons through the air.
Marquise Brown, WR, BAL: Knee -- Active
Impact: Brown and fellow WR Dez Bryant are active, but RB Mark Ingram II again sits.
Cordarrelle Patterson, WR, CHI: Knee -- Active
Impact:, David Montgomery's fantasy output is unlikely to be affected.
Allen Robinson II, WR, CHI: Hamstring -- Active
Impact: Limited practice on Friday, but will give it a go..
Tyler Boyd, WR, CIN: Concussion -- OUT
Impact: A.J. Green could see a few more targets than usual.
Jarvis Landry, WR, CLE: Illness -- OUT/IR
Impact: Landry, Rashard Higgins, Donovan Peoples-Jones and KhaDarel Hodge are all on the reserve/COVID-19 list. Marvin Hall is the last receiver on the team's depth chart to start the week. Ja'Marcus Bradley and Derrick Willies have been elevated from the practice squad.
Duke Johnson, RB, HOU: Neck -- OUT
Impact: David Johnson may once again shine in a dual-purpose role.
Marcus Johnson, WR, IND: Quad -- OUT
Impact: Potential boon for longshot WR options Ashton Dulin/DeMichael Harris.
James Robinson, RB, JAX: Ankle -- OUT
Impact: Dare Ogunbowale and Devine Ozigbo will split carries behind QB Mike Glennon.
Collin Johnson, WR, JAX: Hamstring -- OUT
Impact: Keelan Cole might stumble into a few quality targets.
Clyde Edwards-Helaire, RB, KC: Ankle -- OUT
Impact: Le'Veon Bell/Darrel Williams to fill in for the rest of the regular season.
Tyreek Hill, WR, KC: Hamstring -- Active
Impact: Will start, though if the score allows, he may well get an early hook.
Daniel Jones, QB, NYG: Ankle -- Active
Impact: Will start, but is far from being at 100%.
Golden Tate, WR, NYG: Calf -- OUT
Impact: Sterling Shepard and Darius Slayton will attempt to lift the fortunes of a languid offense.
Chris Boswell, K, PIT: Groin -- Inactive
Impact: Matthew Wright will step in again for the injured kicker
Defense
Darqueze Dennard, CB, ATL: Quad -- OUT
Ricardo Allen, S, ATL: Concussion -- Active
Calais Campbell, DE, BAL: Calf -- Active
Pernell McPhee, LB, BAL: Knee -- Active
Jimmy Smith, CB, BAL: Shoulder -- OUT
Marcus Peters, CB, BAL: Calf -- Inactive
Akiem Hicks, DE, CHI: Ankle -- Active
Mario Edwards, DE, CHI: Hamstring -- Active
Bilal Nichols, DE, CHI: Knee -- Active
Khalil Mack, LB, CHI: Shoulder -- Active
Jaylon Johnson, CB, CHI: Shoulder -- OUT
Logan Wilson, LB, CIN: Ankle -- OUT
Sheldon Richardson, DT, CLE: Neck -- Active
Phillip Gaines, CB, HOU: Knee -- Inactive
Frank Clark, DE, KC: Illness -- Active
Damien Wilson, LB, KC: Knee -- OUT
Blake Martinez, LB, NYG: Ankle -- Active
Darnay Holmes, CB, NYG: Knee -- Active
4 p.m. ET games
Offense
Christian McCaffrey, RB, CAR: Thigh -- Doubtful
Impact: Not yet ruled out, but all signs point to another missed week.
Ezekiel Elliott, RB, DAL: Calf -- Questionable
Impact: Limited in practice this week. Likely to split time with Tony Pollard if active.
Blake Bell, TE, DAL: Illness -- Questionable
Impact: Dalton Schultz has shown flashes of fantasy relevance this season.
Phillip Lindsay, RB, DEN: Hip -- OUT/IR
Impact: Melvin Gordon III likely to get most, if not all, of the workload ....
Royce Freeman, RB, DEN: Hip -- Questionable
Impact: ... as Freeman is also nowhere near full capacity.
Keenan Allen, WR, LAC: Hamstring -- Questionable
Impact: Nowhere near a guaranteed start, Allen did practice a little bit on Friday. Better to assume he will not play.
Hunter Henry, TE, LAC: Illness -- OUT/IR
Impact: Henry is on the reserve/COVID-19 list. Stephen Anderson is not exactly screaming "pick me" as a replacement.
Cam Akers, RB, LAR: Ankle -- OUT
Impact: The tandem of Darrell Henderson and Malcolm Brown will try to shine in Week 16.
Alex Smith, QB, WAS: Calf -- Questionable
Impact: Looking more likely that Dwayne Haskins Jr. will start.
Antonio Gibson, RB, WAS: Toe -- Questionable
Impact: J.D. McKissic's value goes back on the upswing, even if Gibson were to play.
Terry McLaurin, WR, WAS: Ankle -- Doubtful
Impact: For what it's worth, Antonio Gandy-Golden was activated from the IR.
Defense
Brian Burns, DE, CAR: Knee -- Questionable
Bravvion Roy, DT, CAR: Knee -- Questionable
Troy Pride, CB, CAR: Hip -- Doubtful
Antwaun Woods, DT, DAL: Ankle -- OUT
Leighton Vander Esch, LB, DAL: Ankle -- OUT
Xavier Woods, S, DAL: Ribs -- OUT
DeShawn Williams, DT, DEN: Knee -- Questionable
Bradley Chubb, LB, DEN: Ankle -- Questionable
Nate Hairston, S, DEN: Toe -- Questionable
Joey Bosa, DE, LAC: Concussion -- OUT
Uchenna Nwosu, LB, LAC: Knee -- OUT
Fletcher Cox, DT, PHI: Neck -- Questionable
Derek Barnett, DE, PHI: Calf -- Questionable
Duke Riley, LB, PHI: Biceps -- OUT
Kevon Seymour, CB, PHI: Knee -- OUT
Kevin Pierre-Louis, LB, WAS: Ankle -- Questionable
Sunday night game
Jamaal Williams, RB, GB: Quad -- Doubtful
Impact: Aaron Jones (toe) is also a bit banged up but should be active and get the ball early and often.
Jace Sternberger, TE, GB: Concussion -- OUT
Impact: Robert Tonyan still the TE to roll with if you're looking Green Bay's way.